The ApiAP2 factor PfAP2-HC is an integral component of heterochromatin in the malaria parasite Plasmodium falciparum
Summary: Malaria parasites undergo a complex life read more cycle in the human host and the mosquito vector.The ApiAP2 family of DNA-binding proteins plays a dominant role in parasite development and life cycle progression.Most ApiAP2 factors studied to date act as transcription factors regulating stage-specific gene expression.Here, we characteriz